#------------------------------------------------------------------------------ #$Date: 2013-08-29 18:37:19 +0300 (Thu, 29 Aug 2013) $ #$Revision: 88064 $ #$URL: file:///home/coder/svn-repositories/cod/cif/2/01/86/2018696.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/. The original data for this entry # were provided by IUCr Journals, http://journals.iucr.org/. # # The file may be used within the scientific community so long as # proper attribution is given to the journal article from which the # data were obtained. # data_2018696 loop_ _publ_author_name 'Sonar, Vijayakumar N.' 'Parkin, Sean' 'Crooks, Peter A.' _publ_section_title ; The effect of hydrogen bonding on the conformations of 2-(1H-indol-3-yl)-2-oxoacetamide and 2-(1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide ; _journal_coeditor_code YP3017 _journal_issue 10 _journal_name_full 'Acta Crystallographica Section C' _journal_page_first o405 _journal_page_last o407 _journal_volume 68 _journal_year 2012 _chemical_formula_iupac 'C10 H8 N2 O2' _chemical_formula_moiety 'C10 H8 N2 O2' _chemical_formula_sum 'C10 H8 N2 O2' _chemical_formula_weight 188.18 _chemical_name_systematic ; 2-(1H-indol-3-yl)-2-oxoacetamide ; _space_group_IT_number 14 _symmetry_cell_setting monoclinic _symmetry_space_group_name_Hall '-P 2ybc' _symmetry_space_group_name_H-M 'P 1 21/c 1' _atom_sites_solution_hydrogens geom _atom_sites_solution_primary direct _atom_sites_solution_secondary difmap _audit_creation_method SHELXL97 _cell_angle_alpha 90.00 _cell_angle_beta 93.251(3) _cell_angle_gamma 90.00 _cell_formula_units_Z 4 _cell_length_a 5.1253(4) _cell_length_b 19.4363(14) _cell_length_c 8.4953(6) _cell_measurement_reflns_used 8721 _cell_measurement_temperature 90.0(2) _cell_measurement_theta_max 68.95 _cell_measurement_theta_min 4.55 _cell_volume 844.91(11) _computing_cell_refinement 'APEX2 (Bruker, 2006)' _computing_data_collection 'APEX2 (Bruker, 2006)' _computing_data_reduction 'APEX2 (Bruker, 2006)' _computing_molecular_graphics 'XP in SHELXTL (Sheldrick, 2008)' _computing_publication_material ; SHELXL97 (Sheldrick, 2008) and local procedures ; _computing_structure_refinement 'SHELXL97 (Sheldrick, 2008)' _computing_structure_solution 'SHELXS97 (Sheldrick, 2008)' _diffrn_ambient_temperature 90.0(2) _diffrn_detector_area_resol_mean 18 _diffrn_measured_fraction_theta_full 0.964 _diffrn_measured_fraction_theta_max 0.964 _diffrn_measurement_device_type 'Bruker X8 Proteum' _diffrn_measurement_method '\f and \w' _diffrn_radiation_monochromator 'graded multilayer optics' _diffrn_radiation_source 'fine-focus rotating anode' _diffrn_radiation_type CuK\a _diffrn_radiation_wavelength 1.54178 _diffrn_reflns_av_R_equivalents 0.0424 _diffrn_reflns_av_sigmaI/netI 0.0286 _diffrn_reflns_limit_h_max 6 _diffrn_reflns_limit_h_min -4 _diffrn_reflns_limit_k_max 23 _diffrn_reflns_limit_k_min -23 _diffrn_reflns_limit_l_max 10 _diffrn_reflns_limit_l_min -10 _diffrn_reflns_number 10887 _diffrn_reflns_theta_full 68.94 _diffrn_reflns_theta_max 68.94 _diffrn_reflns_theta_min 4.55 _diffrn_standards_number 0 _exptl_absorpt_coefficient_mu 0.880 _exptl_absorpt_correction_T_max 0.949 _exptl_absorpt_correction_T_min 0.744 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; [SADABS (Bruker, 2006) and XABS2 (Parkin et al., 1995)] ; _exptl_crystal_colour colourless _exptl_crystal_density_diffrn 1.479 _exptl_crystal_density_method 'not measured' _exptl_crystal_description needle _exptl_crystal_F_000 392 _exptl_crystal_size_max 0.30 _exptl_crystal_size_mid 0.08 _exptl_crystal_size_min 0.06 _refine_diff_density_max 0.325 _refine_diff_density_min -0.330 _refine_ls_extinction_coef 0.0033(9) _refine_ls_extinction_expression Fc^*^=kFc[1+0.001xFc^2^\l^3^/sin(2\q)]^-1/4^ _refine_ls_extinction_method 'SHELXL97 (Sheldrick, 2008)' _refine_ls_goodness_of_fit_ref 1.235 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 128 _refine_ls_number_reflns 1518 _refine_ls_number_restraints 0 _refine_ls_restrained_S_all 1.235 _refine_ls_R_factor_all 0.0585 _refine_ls_R_factor_gt 0.0575 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'calc w = 1/[\s^2^(Fo^2^)+(0.0370P)^2^+1.8838P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1576 _refine_ls_wR_factor_ref 0.1581 _reflns_number_gt 1481 _reflns_number_total 1518 _reflns_threshold_expression I>2\s(I) _iucr_refine_instructions_details ; TITL I in P2(1)/c CELL 1.54178 5.1253 19.4363 8.4953 90.000 93.251 90.000 ZERR 4.00 0.0004 0.0014 0.0006 0.000 0.003 0.000 LATT 1 SYMM -X, 0.5+Y, 0.5-Z SFAC C H N O UNIT 40 32 8 8 TEMP -183 SIZE 0.30 0.08 0.06 L.S. 4 BOND BOND $H CONF HTAB EQIV $1 x-1, -y+3/2, z+1/2 EQIV $2 -x+1, -y+1, -z+1 EQIV $3 x+1, y, z HTAB N1 O1_$1 HTAB N2 O2_$2 HTAB N2 O2_$3 ACTA FMAP 2 PLAN 10 WGHT 0.037000 1.883800 EXTI 0.003301 FVAR 0.67359 N1 3 0.078234 0.771518 0.555815 11.00000 0.01454 0.03251 = 0.02130 -0.00254 0.00359 0.00380 AFIX 43 H1 2 -0.052943 0.776595 0.617299 11.00000 -1.20000 AFIX 0 N2 3 0.727230 0.560111 0.410322 11.00000 0.00938 0.02114 = 0.03564 0.00276 0.00437 -0.00075 AFIX 93 H2A 2 0.724226 0.516294 0.436239 11.00000 -1.20000 H2B 2 0.876127 0.579961 0.390435 11.00000 -1.20000 AFIX 0 O1 4 0.725312 0.683647 0.268382 11.00000 0.01379 0.02855 = 0.02473 0.00191 0.00718 -0.00030 O2 4 0.291594 0.572395 0.427152 11.00000 0.01200 0.02395 = 0.03353 0.00309 0.00372 -0.00024 C1 1 0.182612 0.711677 0.518140 11.00000 0.01419 0.02691 = 0.01749 0.00013 0.00065 0.00093 AFIX 43 H1A 2 0.128208 0.668057 0.554641 11.00000 -1.20000 AFIX 0 C2 1 0.205396 0.824523 0.484538 11.00000 0.01552 0.02759 = 0.01858 -0.00355 -0.00279 0.00181 C3 1 0.159205 0.894619 0.491757 11.00000 0.02210 0.02946 = 0.03009 -0.00791 -0.00368 0.00433 AFIX 43 H3 2 0.025381 0.912917 0.552409 11.00000 -1.20000 AFIX 0 C4 1 0.316373 0.936660 0.406862 11.00000 0.02740 0.02315 = 0.03748 -0.00300 -0.00713 0.00394 AFIX 43 H4 2 0.288013 0.984962 0.406770 11.00000 -1.20000 AFIX 0 C5 1 0.516341 0.909381 0.321121 11.00000 0.02392 0.02607 = 0.03019 0.00229 -0.00493 -0.00391 AFIX 43 H5 2 0.624939 0.939649 0.266265 11.00000 -1.20000 AFIX 0 C6 1 0.559724 0.839631 0.314261 11.00000 0.01672 0.02684 = 0.02373 0.00049 -0.00161 -0.00119 AFIX 43 H6 2 0.695829 0.821751 0.254803 11.00000 -1.20000 AFIX 0 C7 1 0.400616 0.795622 0.396023 11.00000 0.01295 0.02531 = 0.01710 -0.00012 -0.00244 0.00093 C8 1 0.383408 0.722229 0.417334 11.00000 0.01239 0.02292 = 0.01946 -0.00028 0.00107 0.00146 C9 1 0.546152 0.671197 0.354181 11.00000 0.01179 0.02378 = 0.02001 0.00065 0.00087 -0.00112 C10 1 0.507817 0.596156 0.401251 11.00000 0.01283 0.02449 = 0.02062 -0.00102 0.00276 -0.00030 HKLF 4 REM x07115 in P2(1)/c REM R1 = 0.0575 for 1481 Fo > 4sig(Fo) and 0.0585 for all 1518 data REM 128 parameters refined using 0 restraints END WGHT 0.0370 1.8828 REM Highest difference peak 0.325, deepest hole -0.330, 1-sigma level 0.080 Q1 1 0.4117 0.7574 0.4033 11.00000 0.05 0.32 Q2 1 0.2707 0.7136 0.4532 11.00000 0.05 0.30 Q3 1 0.5485 0.7518 0.1612 11.00000 0.05 0.28 Q4 1 0.2678 0.5197 0.4340 11.00000 0.05 0.27 Q5 1 0.1332 0.8046 0.5064 11.00000 0.05 0.25 Q6 1 0.5973 0.7987 0.1770 11.00000 0.05 0.25 Q7 1 0.1122 0.6133 0.5046 11.00000 0.05 0.24 Q8 1 0.4424 0.7015 0.3995 11.00000 0.05 0.24 Q9 1 0.3267 0.8091 0.4724 11.00000 0.05 0.24 Q10 1 0.2023 0.8545 0.4978 11.00000 0.05 0.23 ; _[local]_cod_data_source_file yp3017.cif _[local]_cod_data_source_block I _[local]_cod_cif_authors_sg_H-M 'P 21/c' _cod_database_code 2018696 loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x, y+1/2, -z+1/2' '-x, -y, -z' 'x, -y-1/2, z-1/2' loop_ _atom_site_type_symbol _atom_site_label _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_calc_flag _atom_site_refinement_flags _atom_site_occupancy _atom_site_symmetry_multiplicity N N1 0.0782(5) 0.77152(13) 0.5558(3) 0.0227(6) Uani d . 1 1 H H1 -0.0529 0.7766 0.6173 0.027 Uiso calc R 1 1 N N2 0.7272(5) 0.56011(12) 0.4103(3) 0.0219(6) Uani d . 1 1 H H2A 0.7242 0.5163 0.4362 0.026 Uiso calc R 1 1 H H2B 0.8761 0.5800 0.3904 0.026 Uiso calc R 1 1 O O1 0.7253(4) 0.68365(10) 0.2684(2) 0.0221(5) Uani d . 1 1 O O2 0.2916(4) 0.57240(10) 0.4272(3) 0.0231(5) Uani d . 1 1 C C1 0.1826(5) 0.71168(15) 0.5181(3) 0.0195(6) Uani d . 1 1 H H1A 0.1282 0.6681 0.5546 0.023 Uiso calc R 1 1 C C2 0.2054(6) 0.82452(15) 0.4845(3) 0.0207(7) Uani d . 1 1 C C3 0.1592(6) 0.89462(16) 0.4918(4) 0.0274(7) Uani d . 1 1 H H3 0.0254 0.9129 0.5524 0.033 Uiso calc R 1 1 C C4 0.3164(6) 0.93666(16) 0.4069(4) 0.0297(8) Uani d . 1 1 H H4 0.2880 0.9850 0.4068 0.036 Uiso calc R 1 1 C C5 0.5163(6) 0.90938(16) 0.3211(4) 0.0270(7) Uani d . 1 1 H H5 0.6249 0.9396 0.2663 0.032 Uiso calc R 1 1 C C6 0.5597(6) 0.83963(15) 0.3143(4) 0.0225(7) Uani d . 1 1 H H6 0.6958 0.8218 0.2548 0.027 Uiso calc R 1 1 C C7 0.4006(5) 0.79562(15) 0.3960(3) 0.0186(6) Uani d . 1 1 C C8 0.3834(5) 0.72223(15) 0.4173(3) 0.0183(6) Uani d . 1 1 C C9 0.5462(5) 0.67120(15) 0.3542(3) 0.0185(6) Uani d . 1 1 C C10 0.5078(5) 0.59616(15) 0.4013(3) 0.0192(6) Uani d . 1 1 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_12 _atom_site_aniso_U_13 _atom_site_aniso_U_23 N1 0.0145(12) 0.0325(14) 0.0213(13) 0.0038(10) 0.0036(10) -0.0025(10) N2 0.0094(11) 0.0211(13) 0.0356(15) -0.0008(9) 0.0044(10) 0.0028(10) O1 0.0138(10) 0.0286(11) 0.0247(11) -0.0003(8) 0.0072(8) 0.0019(8) O2 0.0120(10) 0.0239(11) 0.0335(12) -0.0002(8) 0.0037(8) 0.0031(9) C1 0.0142(14) 0.0269(15) 0.0175(14) 0.0009(11) 0.0007(11) 0.0001(11) C2 0.0155(14) 0.0276(16) 0.0186(15) 0.0018(11) -0.0028(11) -0.0035(11) C3 0.0221(16) 0.0295(17) 0.0301(18) 0.0043(13) -0.0037(13) -0.0079(13) C4 0.0274(17) 0.0231(16) 0.0375(19) 0.0039(13) -0.0071(14) -0.0030(13) C5 0.0239(16) 0.0261(16) 0.0302(18) -0.0039(12) -0.0049(13) 0.0023(13) C6 0.0167(15) 0.0268(16) 0.0237(16) -0.0012(12) -0.0016(12) 0.0005(12) C7 0.0130(13) 0.0253(15) 0.0171(14) 0.0009(11) -0.0024(11) -0.0001(11) C8 0.0124(13) 0.0229(14) 0.0195(14) 0.0015(11) 0.0011(11) -0.0003(11) C9 0.0118(13) 0.0238(15) 0.0200(15) -0.0011(11) 0.0009(11) 0.0007(11) C10 0.0128(14) 0.0245(15) 0.0206(15) -0.0003(11) 0.0028(11) -0.0010(11) loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0181 0.0091 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' N N 0.0311 0.0180 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0492 0.0322 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_publ_flag C1 N1 C2 110.0(2) ? C1 N1 H1 125.0 ? C2 N1 H1 125.0 ? C10 N2 H2A 120.0 ? C10 N2 H2B 120.0 ? H2A N2 H2B 120.0 ? N1 C1 C8 110.0(3) ? N1 C1 H1A 125.0 ? C8 C1 H1A 125.0 ? N1 C2 C3 129.1(3) ? N1 C2 C7 107.8(3) ? C3 C2 C7 123.1(3) ? C4 C3 C2 117.0(3) ? C4 C3 H3 121.5 ? C2 C3 H3 121.5 ? C3 C4 C5 121.1(3) ? C3 C4 H4 119.5 ? C5 C4 H4 119.5 ? C6 C5 C4 121.5(3) ? C6 C5 H5 119.3 ? C4 C5 H5 119.3 ? C5 C6 C7 118.9(3) ? C5 C6 H6 120.6 ? C7 C6 H6 120.6 ? C6 C7 C2 118.5(3) ? C6 C7 C8 135.4(3) ? C2 C7 C8 106.2(2) ? C1 C8 C9 126.9(3) y C1 C8 C7 106.0(2) ? C9 C8 C7 127.0(3) ? O1 C9 C8 124.1(3) y O1 C9 C10 117.1(3) y C8 C9 C10 118.7(2) ? O2 C10 N2 124.1(3) y O2 C10 C9 122.3(2) y N2 C10 C9 113.5(2) y loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_publ_flag N1 C1 1.327(4) ? N1 C2 1.378(4) ? N1 H1 0.8800 ? N2 C10 1.323(4) y N2 H2A 0.8800 ? N2 H2B 0.8800 ? O1 C9 1.228(3) ? O2 C10 1.232(3) y C1 C8 1.391(4) ? C1 H1A 0.9500 ? C2 C3 1.385(4) ? C2 C7 1.403(4) ? C3 C4 1.379(5) ? C3 H3 0.9500 ? C4 C5 1.395(5) ? C4 H4 0.9500 ? C5 C6 1.376(4) ? C5 H5 0.9500 ? C6 C7 1.394(4) ? C6 H6 0.9500 ? C7 C8 1.441(4) ? C8 C9 1.421(4) y C9 C10 1.528(4) y loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_site_symmetry_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA N1 H1 O1 4_476 0.88 1.92 2.768(3) 160.2 N2 H2A O2 3_666 0.88 2.08 2.926(3) 160.5 N2 H2B O2 1_655 0.88 2.14 2.898(3) 144.0 loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion _geom_torsion_publ_flag C2 N1 C1 C8 -0.9(3) ? C1 N1 C2 C3 179.8(3) ? C1 N1 C2 C7 0.4(3) ? N1 C2 C3 C4 -179.5(3) ? C7 C2 C3 C4 -0.2(4) ? C2 C3 C4 C5 -1.5(5) ? C3 C4 C5 C6 1.9(5) ? C4 C5 C6 C7 -0.4(5) ? C5 C6 C7 C2 -1.2(4) ? C5 C6 C7 C8 179.8(3) ? N1 C2 C7 C6 -179.0(3) ? C3 C2 C7 C6 1.5(4) ? N1 C2 C7 C8 0.2(3) ? C3 C2 C7 C8 -179.2(3) ? N1 C1 C8 C9 178.3(3) ? N1 C1 C8 C7 1.0(3) ? C6 C7 C8 C1 178.4(3) ? C2 C7 C8 C1 -0.7(3) ? C6 C7 C8 C9 1.0(5) ? C2 C7 C8 C9 -178.1(3) ? C1 C8 C9 O1 -178.2(3) y C7 C8 C9 O1 -1.3(5) ? C1 C8 C9 C10 -1.4(4) ? C7 C8 C9 C10 175.5(3) ? O1 C9 C10 O2 -149.3(3) y C8 C9 C10 O2 33.7(4) ? O1 C9 C10 N2 30.4(4) ? C8 C9 C10 N2 -146.6(3) ? _cod_database_fobs_code 2018696