#------------------------------------------------------------------------------ #$Date: 2008-04-03 13:11:48 +0300 (Thu, 03 Apr 2008) $ #$Revision: 326 $ #$URL: file:///home/coder/svn-repositories/cod/cif/2/2208742.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/. The original data for this entry # were provided by IUCr Journals, http://journals.iucr.org/. # # The file may be used within the scientific community so long as # proper attribution is given to the journal article from which the # data were obtained. # data_2208742 loop_ _publ_author_name 'C\'esar D. de Oliveira' 'Gilberto A. Romeiro' 'Janet M. S. Skakle' 'James L. Wardell' 'Solange M. S. V. Wardell' _publ_section_title ; Ethyl 5-chloro-9-ethoxy-2-oxo-2H-pyrano[2,3-g]quinoline-8-carboxylate ; _journal_coeditor_code WK2004 _journal_issue 4 _journal_name_full 'Acta Crystallographica, Section E' _journal_page_first o1494 _journal_page_last o1495 _journal_volume 62 _journal_year 2006 _chemical_formula_iupac 'C17 H14 Cl N O5' _chemical_formula_moiety 'C17 H14 Cl N O5' _chemical_formula_sum 'C17 H14 Cl N O5' _chemical_formula_weight 347.74 _chemical_name_systematic ; Ethyl 5-chloro-9-ethoxy-2-oxo-2H-pyrano[2,3-g]quinoline-8-carboxylate ; _symmetry_cell_setting orthorhombic _symmetry_space_group_name_Hall 'P 2c -2n' _symmetry_space_group_name_H-M 'P n a 21' _atom_sites_solution_hydrogens geom _atom_sites_solution_primary direct _atom_sites_solution_secondary difmap _audit_creation_method SHELXL-97 _cell_angle_alpha 90.00 _cell_angle_beta 90.00 _cell_angle_gamma 90.00 _cell_formula_units_Z 4 _cell_length_a 7.1480(9) _cell_length_b 19.653(3) _cell_length_c 11.1150(14) _cell_measurement_reflns_used 1346 _cell_measurement_temperature 291(2) _cell_measurement_theta_max 19.2505 _cell_measurement_theta_min 3.5245 _cell_volume 1561.4(3) _computing_cell_refinement 'SAINT (Bruker, 2000)' _computing_data_collection 'SMART (Bruker, 1998)' _computing_data_reduction SAINT _computing_molecular_graphics ; ORTEP-3 for Windows (Farrugia, 1997) ; _computing_publication_material 'CIFTAB (Sheldrick, 1997)' _computing_structure_refinement ; OSCAIL and SHELXL97 (Sheldrick, 1997) ; _computing_structure_solution ; OSCAIL (McArdle, 2003) and SHELXS97 (Sheldrick, 1997) ; _diffrn_ambient_temperature 291(2) _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 1.000 _diffrn_measurement_device_type 'Bruker SMART 1000 CCD area-detector' _diffrn_measurement_method \w _diffrn_radiation_monochromator graphite _diffrn_radiation_source 'fine-focus sealed tube' _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_reflns_av_R_equivalents 0.0999 _diffrn_reflns_av_sigmaI/netI 0.1567 _diffrn_reflns_limit_h_max 10 _diffrn_reflns_limit_h_min -10 _diffrn_reflns_limit_k_max 29 _diffrn_reflns_limit_k_min -29 _diffrn_reflns_limit_l_max 13 _diffrn_reflns_limit_l_min -16 _diffrn_reflns_number 15310 _diffrn_reflns_theta_full 32.52 _diffrn_reflns_theta_max 32.52 _diffrn_reflns_theta_min 2.07 _diffrn_standards_decay_% 0 _diffrn_standards_number 0 _exptl_absorpt_coefficient_mu 0.273 _exptl_absorpt_correction_T_max 0.995 _exptl_absorpt_correction_T_min 0.866 _exptl_absorpt_correction_type multi-scan _exptl_crystal_colour clear _exptl_crystal_density_diffrn 1.479 _exptl_crystal_density_method 'not measured' _exptl_crystal_description needle _exptl_crystal_F_000 720 _exptl_crystal_size_max 0.38 _exptl_crystal_size_mid 0.10 _exptl_crystal_size_min 0.02 _refine_diff_density_max 0.269 _refine_diff_density_min -0.165 _refine_ls_abs_structure_details 'Flack (1983)' _refine_ls_abs_structure_Flack 0.00(7) _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 0.791 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 219 _refine_ls_number_reflns 5017 _refine_ls_number_restraints 1 _refine_ls_restrained_S_all 0.791 _refine_ls_R_factor_all 0.2017 _refine_ls_R_factor_gt 0.0518 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0131P)^2^] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.0554 _refine_ls_wR_factor_ref 0.0756 _reflns_number_gt 1745 _reflns_number_total 5017 _reflns_threshold_expression I>2\s(I) _[local]_cod_data_source_file wk2004.cif loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x, -y, z+1/2' 'x+1/2, -y+1/2, z' '-x+1/2, y+1/2, z+1/2' loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' Cl Cl 0.1484 0.1585 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' N N 0.0061 0.0033 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _atom_site_type_symbol _atom_site_label _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_calc_flag _atom_site_refinement_flags _atom_site_occupancy C C1 0.5477(4) 0.26739(15) 0.7928(2) 0.0384(8) Uani d . 1 C C2 0.5707(5) 0.32697(15) 0.8673(2) 0.0396(9) Uani d . 1 O O2 0.6140(3) 0.31280(9) 0.98103(16) 0.0554(6) Uani d . 1 C C21 0.7298(5) 0.35674(14) 1.0542(3) 0.0515(9) Uani d . 1 H H21A 0.6546 0.3921 1.0911 0.062 Uiso calc R 1 H H21B 0.8259 0.3780 1.0054 0.062 Uiso calc R 1 C C22 0.8169(5) 0.31246(17) 1.1489(3) 0.0742(11) Uani d . 1 H H22A 0.7203 0.2894 1.1929 0.111 Uiso calc R 1 H H22B 0.8887 0.3401 1.2031 0.111 Uiso calc R 1 H H22C 0.8972 0.2796 1.1114 0.111 Uiso calc R 1 C C3 0.5482(4) 0.38991(15) 0.8139(3) 0.0394(8) Uani d . 1 C C31 0.5414(5) 0.45618(17) 0.8800(3) 0.0492(9) Uani d . 1 O O31 0.6132(4) 0.50542(10) 0.81272(17) 0.0627(7) Uani d . 1 O O32 0.4740(3) 0.46481(10) 0.9783(2) 0.0691(7) Uani d . 1 C C32 0.5921(6) 0.57510(16) 0.8570(3) 0.0734(12) Uani d . 1 H H32A 0.6493 0.5799 0.9357 0.088 Uiso calc R 1 H H32B 0.4608 0.5871 0.8632 0.088 Uiso calc R 1 C C33 0.6887(5) 0.61997(15) 0.7671(3) 0.0808(13) Uani d . 1 H H33A 0.8192 0.6086 0.7642 0.121 Uiso calc R 1 H H33B 0.6745 0.6667 0.7906 0.121 Uiso calc R 1 H H33C 0.6340 0.6133 0.6891 0.121 Uiso calc R 1 C C4 0.5045(4) 0.39197(14) 0.6895(3) 0.0448(9) Uani d . 1 H H4 0.4947 0.4348 0.6544 0.054 Uiso calc R 1 N N5 0.4765(4) 0.33948(13) 0.6193(2) 0.0460(7) Uani d . 1 C C6 0.4954(4) 0.27698(14) 0.6713(2) 0.0383(7) Uani d . 1 C C7 0.4651(4) 0.21757(16) 0.6005(2) 0.0430(8) Uani d . 1 Cl Cl7 0.39837(12) 0.22796(4) 0.45262(8) 0.0614(2) Uani d . 1 C C8 0.4881(4) 0.15307(15) 0.6457(3) 0.0403(8) Uani d . 1 C C9 0.4591(4) 0.09056(16) 0.5782(3) 0.0516(9) Uani d . 1 H H9 0.4179 0.0926 0.4989 0.062 Uiso calc R 1 C C10 0.4911(5) 0.03104(17) 0.6289(3) 0.0591(10) Uani d . 1 H H10 0.4684 -0.0082 0.5843 0.071 Uiso calc R 1 C C11 0.5598(5) 0.02387(17) 0.7506(3) 0.0586(10) Uani d . 1 O O11 0.6028(4) -0.02798(11) 0.8000(2) 0.0799(9) Uani d . 1 O O12 0.5750(3) 0.08350(10) 0.81648(17) 0.0533(6) Uani d . 1 C C13 0.5440(4) 0.14710(14) 0.7658(3) 0.0417(8) Uani d . 1 C C14 0.5745(4) 0.20186(14) 0.8390(2) 0.0417(8) Uani d . 1 H H14 0.6123 0.1957 0.9183 0.050 Uiso calc R 1 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_12 _atom_site_aniso_U_13 _atom_site_aniso_U_23 C1 0.040(2) 0.0420(19) 0.0329(17) -0.0042(16) 0.0025(14) 0.0021(15) C2 0.037(2) 0.049(2) 0.0322(18) -0.0073(16) -0.0010(14) 0.0006(15) O2 0.0779(18) 0.0508(13) 0.0374(14) -0.0159(12) -0.0108(12) 0.0064(10) C21 0.060(3) 0.055(2) 0.039(2) -0.0083(18) -0.0076(16) -0.0096(15) C22 0.094(3) 0.075(2) 0.054(2) 0.000(2) -0.022(2) 0.0072(18) C3 0.042(2) 0.045(2) 0.0313(18) -0.0024(15) 0.0027(15) -0.0029(14) C31 0.060(3) 0.043(2) 0.045(2) 0.0036(19) -0.0045(18) 0.0000(17) O31 0.094(2) 0.0416(14) 0.0527(14) -0.0067(14) 0.0116(12) -0.0089(11) O32 0.102(2) 0.0574(14) 0.0482(17) 0.0106(14) 0.0127(15) -0.0039(11) C32 0.104(3) 0.040(2) 0.076(3) 0.001(2) 0.005(2) -0.0202(18) C33 0.108(4) 0.043(2) 0.091(3) -0.003(2) -0.002(3) -0.002(2) C4 0.051(2) 0.0366(18) 0.047(2) 0.0034(17) -0.0014(16) 0.0078(16) N5 0.056(2) 0.0437(16) 0.0382(16) 0.0017(13) -0.0065(13) 0.0011(13) C6 0.047(2) 0.0358(18) 0.0323(16) -0.0019(16) -0.0014(14) -0.0012(15) C7 0.038(2) 0.063(2) 0.0277(16) -0.0005(17) -0.0046(14) -0.0009(15) Cl7 0.0839(7) 0.0643(5) 0.0361(4) 0.0005(5) -0.0135(5) -0.0033(4) C8 0.041(2) 0.0401(19) 0.0400(19) -0.0002(16) 0.0013(15) -0.0015(15) C9 0.063(3) 0.052(2) 0.0397(19) -0.0050(19) 0.0057(17) -0.0111(16) C10 0.083(3) 0.042(2) 0.053(2) -0.003(2) -0.001(2) -0.0132(17) C11 0.070(3) 0.043(2) 0.062(3) -0.003(2) 0.004(2) -0.0017(19) O11 0.110(3) 0.0407(16) 0.0885(18) 0.0019(16) -0.0146(16) 0.0038(14) O12 0.0716(18) 0.0401(13) 0.0482(13) -0.0033(13) -0.0040(12) 0.0032(10) C13 0.044(2) 0.041(2) 0.0396(19) -0.0001(16) 0.0024(16) 0.0050(15) C14 0.045(2) 0.0415(19) 0.0383(17) -0.0061(16) -0.0019(15) 0.0011(15) loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance C1 C14 1.400(3) C1 C6 1.414(4) C1 C2 1.444(4) C2 O2 1.331(3) C2 C3 1.381(4) O2 C21 1.446(3) C21 C22 1.501(4) C21 H21A 0.9700 C21 H21B 0.9700 C22 H22A 0.9600 C22 H22B 0.9600 C22 H22C 0.9600 C3 C4 1.418(4) C3 C31 1.497(4) C31 O32 1.206(3) C31 O31 1.326(3) O31 C32 1.463(3) C32 C33 1.500(4) C32 H32A 0.9700 C32 H32B 0.9700 C33 H33A 0.9600 C33 H33B 0.9600 C33 H33C 0.9600 C4 N5 1.309(3) C4 H4 0.9300 N5 C6 1.364(3) C6 C7 1.425(3) C7 C8 1.373(4) C7 Cl7 1.724(3) C8 C13 1.399(4) C8 C9 1.454(4) C9 C10 1.318(4) C9 H9 0.9300 C10 C11 1.446(4) C10 H10 0.9300 C11 O11 1.198(3) C11 O12 1.386(3) O12 C13 1.389(3) C13 C14 1.367(3) C14 H14 0.9300 loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle C14 C1 C6 120.6(3) C14 C1 C2 121.3(3) C6 C1 C2 118.0(3) O2 C2 C3 128.5(3) O2 C2 C1 113.7(3) C3 C2 C1 117.8(3) C2 O2 C21 122.8(2) O2 C21 C22 106.6(2) O2 C21 H21A 110.4 C22 C21 H21A 110.4 O2 C21 H21B 110.4 C22 C21 H21B 110.4 H21A C21 H21B 108.6 C21 C22 H22A 109.5 C21 C22 H22B 109.5 H22A C22 H22B 109.5 C21 C22 H22C 109.5 H22A C22 H22C 109.5 H22B C22 H22C 109.5 C2 C3 C4 118.1(3) C2 C3 C31 124.9(3) C4 C3 C31 116.6(3) O32 C31 O31 124.3(3) O32 C31 C3 125.5(3) O31 C31 C3 110.2(3) C31 O31 C32 117.0(2) O31 C32 C33 106.2(2) O31 C32 H32A 110.5 C33 C32 H32A 110.5 O31 C32 H32B 110.5 C33 C32 H32B 110.5 H32A C32 H32B 108.7 C32 C33 H33A 109.5 C32 C33 H33B 109.5 H33A C33 H33B 109.5 C32 C33 H33C 109.5 H33A C33 H33C 109.5 H33B C33 H33C 109.5 N5 C4 C3 126.3(3) N5 C4 H4 116.8 C3 C4 H4 116.8 C4 N5 C6 116.2(3) N5 C6 C1 123.4(3) N5 C6 C7 119.3(3) C1 C6 C7 117.3(3) C8 C7 C6 122.4(3) C8 C7 Cl7 119.4(2) C6 C7 Cl7 118.2(2) C7 C8 C13 117.4(3) C7 C8 C9 125.0(3) C13 C8 C9 117.5(3) C10 C9 C8 120.3(3) C10 C9 H9 119.8 C8 C9 H9 119.8 C9 C10 C11 123.0(3) C9 C10 H10 118.5 C11 C10 H10 118.5 O11 C11 O12 117.2(3) O11 C11 C10 126.8(3) O12 C11 C10 116.0(3) C11 O12 C13 122.3(2) C14 C13 O12 116.2(3) C14 C13 C8 123.2(3) O12 C13 C8 120.5(3) C13 C14 C1 119.0(3) C13 C14 H14 120.5 C1 C14 H14 120.5 loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion C14 C1 C2 O2 -1.5(4) C6 C1 C2 O2 177.9(3) C14 C1 C2 C3 177.8(3) C6 C1 C2 C3 -2.8(4) C3 C2 O2 C21 -31.0(5) C1 C2 O2 C21 148.2(3) C2 O2 C21 C22 -154.9(3) O2 C2 C3 C4 179.0(3) C1 C2 C3 C4 -0.2(4) O2 C2 C3 C31 -9.4(5) C1 C2 C3 C31 171.4(3) C2 C3 C31 O32 -34.8(6) C4 C3 C31 O32 136.9(4) C2 C3 C31 O31 148.0(3) C4 C3 C31 O31 -40.3(4) O32 C31 O31 C32 -5.9(5) C3 C31 O31 C32 171.3(3) C31 O31 C32 C33 178.5(3) C2 C3 C4 N5 2.5(5) C31 C3 C4 N5 -169.8(3) C3 C4 N5 C6 -1.4(5) C4 N5 C6 C1 -1.9(5) C4 N5 C6 C7 179.3(3) C14 C1 C6 N5 -176.6(3) C2 C1 C6 N5 4.0(5) C14 C1 C6 C7 2.2(4) C2 C1 C6 C7 -177.2(3) N5 C6 C7 C8 177.6(3) C1 C6 C7 C8 -1.2(4) N5 C6 C7 Cl7 -2.0(4) C1 C6 C7 Cl7 179.2(2) C6 C7 C8 C13 -0.2(5) Cl7 C7 C8 C13 179.4(2) C6 C7 C8 C9 179.9(3) Cl7 C7 C8 C9 -0.5(4) C7 C8 C9 C10 177.7(3) C13 C8 C9 C10 -2.2(4) C8 C9 C10 C11 -1.6(5) C9 C10 C11 O11 -175.1(4) C9 C10 C11 O12 5.6(5) O11 C11 O12 C13 174.6(3) C10 C11 O12 C13 -6.1(4) C11 O12 C13 C14 -176.3(3) C11 O12 C13 C8 2.6(4) C7 C8 C13 C14 0.6(5) C9 C8 C13 C14 -179.5(3) C7 C8 C13 O12 -178.2(3) C9 C8 C13 O12 1.7(4) O12 C13 C14 C1 179.3(3) C8 C13 C14 C1 0.4(5) C6 C1 C14 C13 -1.8(4) C2 C1 C14 C13 177.6(3) loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_site_symmetry_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA C9 H9 O11 2_654 0.93 2.55 3.357(4) 145 C4 H4 O31 . 0.93 2.40 2.730(4) 101 C9 H9 Cl7 . 0.93 2.71 3.071(3) 104 C21 H21A O32 . 0.97 2.30 2.927(4) 122