#------------------------------------------------------------------------------ #$Date: 2013-12-28 15:58:47 +0200 (Sat, 28 Dec 2013) $ #$Revision: 91933 $ #$URL: file:///home/coder/svn-repositories/cod/cif/2/21/66/2216643.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/. The original data for this entry # were provided by IUCr Journals, http://journals.iucr.org/. # # The file may be used within the scientific community so long as # proper attribution is given to the journal article from which the # data were obtained. # data_2216643 loop_ _publ_author_name 'Wen-jing Li' 'Rong Li' 'Wen-Qin Wang' 'Ying Zhong' _publ_section_title 2-Butylamino-3-(4-fluorophenyl)-6,8-diphenyl-3,5,6,8-tetrahydro-4H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-one _journal_coeditor_code LH2571 _journal_issue 12 _journal_name_full 'Acta Crystallographica Section E' _journal_page_first o4869 _journal_page_last o4869 _journal_volume 63 _journal_year 2007 _chemical_formula_iupac 'C31 H28 F N3 O S2' _chemical_formula_moiety 'C31 H28 F N3 O S2' _chemical_formula_sum 'C31 H28 F N3 O S2' _chemical_formula_weight 541.68 _chemical_name_systematic ; 2-Butylamino-3-(4-fluorophenyl)-6,8-diphenyl-3,5,6,8-tetrahydro- 4H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-one ; _space_group_IT_number 14 _symmetry_cell_setting monoclinic _symmetry_space_group_name_Hall '-P 2ybc' _symmetry_space_group_name_H-M 'P 1 21/c 1' _atom_sites_solution_hydrogens geom _atom_sites_solution_primary direct _atom_sites_solution_secondary difmap _audit_creation_method SHELXL-97 _cell_angle_alpha 90.00 _cell_angle_beta 107.916(2) _cell_angle_gamma 90.00 _cell_formula_units_Z 4 _cell_length_a 12.9430(10) _cell_length_b 19.2323(15) _cell_length_c 11.9433(19) _cell_measurement_reflns_used 7165 _cell_measurement_temperature 294(2) _cell_measurement_theta_max 26.59 _cell_measurement_theta_min 2.29 _cell_volume 2828.8(5) _computing_cell_refinement 'SAINT-Plus (Bruker, 2001)' _computing_data_collection 'SMART (Bruker, 2001)' _computing_data_reduction 'SAINT-Plus (Bruker, 2001)' _computing_molecular_graphics 'PLATON (Spek, 2003)' _computing_publication_material 'SHELXTL (Sheldrick, 2001)' _computing_structure_refinement 'SHELXL97 (Sheldrick, 1997)' _computing_structure_solution 'SHELXS97 (Sheldrick, 1997)' _diffrn_ambient_temperature 294(2) _diffrn_measured_fraction_theta_full 0.987 _diffrn_measured_fraction_theta_max 0.987 _diffrn_measurement_device_type 'Bruker SMART 4K CCD area-detector' _diffrn_measurement_method '\f and \w scans' _diffrn_radiation_monochromator graphite _diffrn_radiation_source 'fine-focus sealed tube' _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_reflns_av_R_equivalents 0.0386 _diffrn_reflns_av_sigmaI/netI 0.0311 _diffrn_reflns_limit_h_max 15 _diffrn_reflns_limit_h_min -15 _diffrn_reflns_limit_k_max 22 _diffrn_reflns_limit_k_min -22 _diffrn_reflns_limit_l_max 12 _diffrn_reflns_limit_l_min -14 _diffrn_reflns_number 22538 _diffrn_reflns_theta_full 25.00 _diffrn_reflns_theta_max 25.00 _diffrn_reflns_theta_min 1.65 _exptl_absorpt_coefficient_mu 0.224 _exptl_absorpt_correction_T_max 0.9780 _exptl_absorpt_correction_T_min 0.9567 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details '(SADABS; Sheldrick, 2003)' _exptl_crystal_colour colorless _exptl_crystal_density_diffrn 1.272 _exptl_crystal_density_method 'not measured' _exptl_crystal_description block _exptl_crystal_F_000 1136 _exptl_crystal_size_max 0.20 _exptl_crystal_size_mid 0.10 _exptl_crystal_size_min 0.10 _refine_diff_density_max 0.387 _refine_diff_density_min -0.330 _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.040 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 361 _refine_ls_number_reflns 4926 _refine_ls_number_restraints 6 _refine_ls_restrained_S_all 1.049 _refine_ls_R_factor_all 0.0854 _refine_ls_R_factor_gt 0.0631 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'calc w=1/[\s^2^(Fo^2^)+(0.1581P)^2^+0.0000P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1886 _refine_ls_wR_factor_ref 0.2177 _reflns_number_gt 3496 _reflns_number_total 4926 _reflns_threshold_expression I>2\s(I) _[local]_cod_data_source_file lh2571.cif _[local]_cod_data_source_block I _[local]_cod_cif_authors_sg_H-M 'P 21/c' _cod_depositor_comments ; The following automatic conversions were performed: '_symmetry_cell_setting' value 'Monoclinic' changed to 'monoclinic' according to '/home/saulius/struct/CIF-dictionaries/cif_core.dic' dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29. Automatic conversion script Id: cif_fix_enum 1527 2010-12-29 10:47:43Z saulius The following automatic conversions were performed: '_symmetry_cell_setting' value 'Monoclinic' changed to 'monoclinic' according to /home/saulius/struct/CIF-dictionaries/cif_core.dic dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29. Automatic conversion script Id: cif_fix_values 1715 2011-07-08 13:25:40Z adriana ; _cod_database_code 2216643 loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x, y+1/2, -z+1/2' '-x, -y, -z' 'x, -y-1/2, z-1/2' loop_ _atom_site_type_symbol _atom_site_label _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_calc_flag _atom_site_refinement_flags _atom_site_occupancy _atom_site_disorder_assembly _atom_site_disorder_group C C1 0.8214(2) 0.48052(16) 0.6797(2) 0.0546(7) Uani d . 1 . . H H1 0.7860 0.5241 0.6460 0.066 Uiso calc R 1 . . C C2 0.7483(2) 0.44333(16) 0.7389(2) 0.0540(7) Uani d . 1 . . H H2A 0.7838 0.4010 0.7756 0.065 Uiso calc R 1 . . H H2B 0.7377 0.4729 0.8003 0.065 Uiso calc R 1 . . C C3 0.6392(2) 0.42529(13) 0.6531(2) 0.0445(6) Uani d . 1 . . C C4 0.6206(2) 0.41847(13) 0.5352(2) 0.0467(6) Uani d . 1 . . C C5 0.6986(2) 0.42672(14) 0.4652(2) 0.0499(7) Uani d . 1 . . H H5 0.6839 0.4714 0.4239 0.060 Uiso calc R 1 . . C C6 0.9332(3) 0.49748(18) 0.7595(3) 0.0620(8) Uani d . 1 . . C C7 0.9944(3) 0.4521(3) 0.8420(3) 0.0891(12) Uani d . 1 . . H H7 0.9663 0.4086 0.8507 0.107 Uiso calc R 1 . . C C8 1.0967(4) 0.4700(3) 0.9120(4) 0.1054(15) Uani d . 1 . . H H8 1.1363 0.4382 0.9675 0.126 Uiso calc R 1 . . C C9 1.1408(4) 0.5315(3) 0.9027(4) 0.1058(16) Uani d . 1 . . H H9 1.2107 0.5424 0.9497 0.127 Uiso calc R 1 . . C C10 1.0824(5) 0.5770(4) 0.8244(6) 0.151(3) Uani d . 1 . . H H10 1.1117 0.6203 0.8173 0.181 Uiso calc R 1 . . C C11 0.9783(4) 0.5607(3) 0.7533(5) 0.1189(19) Uani d . 1 . . H H11 0.9387 0.5937 0.7005 0.143 Uiso calc R 1 . . C C12 0.6877(2) 0.36995(15) 0.3746(2) 0.0498(7) Uani d . 1 . . C C13 0.6964(3) 0.30109(16) 0.4072(3) 0.0716(10) Uani d . 1 . . H H13 0.7111 0.2893 0.4861 0.086 Uiso calc R 1 . . C C14 0.6836(4) 0.2490(2) 0.3238(3) 0.0862(12) Uani d . 1 . . H H14 0.6888 0.2026 0.3466 0.103 Uiso calc R 1 . . C C15 0.6632(4) 0.2661(2) 0.2081(3) 0.0889(13) Uani d . 1 . . H H15 0.6549 0.2312 0.1521 0.107 Uiso calc R 1 . . C C16 0.6550(3) 0.3340(2) 0.1742(3) 0.0833(12) Uani d . 1 . . H H16 0.6412 0.3453 0.0953 0.100 Uiso calc R 1 . . C C17 0.6673(3) 0.38626(18) 0.2573(3) 0.0640(8) Uani d . 1 . . H H17 0.6616 0.4326 0.2338 0.077 Uiso calc R 1 . . C C18 0.5413(2) 0.41524(13) 0.6844(2) 0.0419(6) Uani d . 1 . . C C19 0.4515(2) 0.40394(13) 0.5888(2) 0.0456(6) Uani d . 1 . . C C20 0.5285(2) 0.41069(13) 0.7992(2) 0.0443(6) Uani d . 1 . . C C21 0.3346(2) 0.39246(15) 0.6934(2) 0.0497(7) Uani d . 1 . . C C22 0.4028(2) 0.37698(14) 0.9065(2) 0.0473(6) Uani d . 1 . . C C23 0.3956(2) 0.42682(15) 0.9860(2) 0.0528(7) Uani d . 1 . . H H23 0.4021 0.4736 0.9697 0.063 Uiso calc R 1 . . C C24 0.3788(3) 0.40724(17) 1.0902(3) 0.0625(8) Uani d . 1 . . H H24 0.3762 0.4402 1.1462 0.075 Uiso calc R 1 . . C C25 0.3661(3) 0.33909(18) 1.1087(3) 0.0667(9) Uani d . 1 . . C C26 0.3731(3) 0.28827(18) 1.0313(3) 0.0728(10) Uani d . 1 . . H H26 0.3643 0.2417 1.0472 0.087 Uiso calc R 1 . . C C27 0.3936(3) 0.30789(15) 0.9292(3) 0.0617(8) Uani d . 1 . . H H27 0.4011 0.2744 0.8760 0.074 Uiso calc R 1 . . C C28 0.1356(3) 0.3866(3) 0.6054(4) 0.1014(15) Uani d D 1 . . H H28A 0.1406 0.4237 0.5523 0.122 Uiso calc PR 0.604(7) A 1 H H28B 0.0760 0.3982 0.6353 0.122 Uiso calc PR 0.604(7) A 1 H H28C 0.1492 0.4031 0.5345 0.122 Uiso d PR 0.396(7) A 2 H H28D 0.0800 0.4154 0.6209 0.122 Uiso d PR 0.396(7) A 2 C C29 0.1060(9) 0.3233(6) 0.5360(7) 0.132(3) Uani d PD 0.604(7) A 1 H H29A 0.1650 0.3077 0.5081 0.159 Uiso calc PR 0.604(7) A 1 H H29B 0.0420 0.3306 0.4688 0.159 Uiso calc PR 0.604(7) A 1 C C30 0.0837(12) 0.2715(7) 0.6196(11) 0.168(4) Uani d PD 0.604(7) A 1 H H30A 0.0338 0.2897 0.6586 0.202 Uiso calc PR 0.604(7) A 1 H H30B 0.1498 0.2561 0.6780 0.202 Uiso calc PR 0.604(7) A 1 C C31 0.0308(18) 0.2126(10) 0.5299(17) 0.270(10) Uani d PD 0.604(7) A 1 H H31A 0.0860 0.1896 0.5053 0.405 Uiso calc PR 0.604(7) A 1 H H31B -0.0220 0.2326 0.4626 0.405 Uiso calc PR 0.604(7) A 1 H H31C -0.0041 0.1796 0.5666 0.405 Uiso calc PR 0.604(7) A 1 C C29' 0.0978(16) 0.3103(7) 0.5937(13) 0.132(3) Uani d PD 0.396(7) A 2 H H29C 0.1595 0.2819 0.5928 0.159 Uiso calc PR 0.396(7) A 2 H H29D 0.0802 0.2984 0.6647 0.159 Uiso calc PR 0.396(7) A 2 C C30' 0.0013(13) 0.2882(10) 0.4884(16) 0.168(4) Uani d PD 0.396(7) A 2 H H30C -0.0566 0.2739 0.5190 0.202 Uiso calc PR 0.396(7) A 2 H H30D -0.0241 0.3293 0.4408 0.202 Uiso calc PR 0.396(7) A 2 C C31' 0.016(2) 0.2310(14) 0.406(2) 0.231(13) Uani d PD 0.396(7) A 2 H H31D -0.0515 0.2241 0.3447 0.346 Uiso calc PR 0.396(7) A 2 H H31E 0.0364 0.1887 0.4500 0.346 Uiso calc PR 0.396(7) A 2 H H31F 0.0711 0.2443 0.3726 0.346 Uiso calc PR 0.396(7) A 2 F F1 0.3479(2) 0.31934(13) 1.21011(16) 0.0997(8) Uani d . 1 . . N N1 0.41996(19) 0.39625(11) 0.79666(19) 0.0470(6) Uani d . 1 . . N N2 0.34648(19) 0.39482(12) 0.58824(19) 0.0496(6) Uani d . 1 . . N N3 0.2334(2) 0.38759(16) 0.7029(2) 0.0711(8) Uani d . 1 A . H H3 0.2273 0.3849 0.7725 0.085 Uiso calc R 1 . . O O1 0.59961(17) 0.41631(10) 0.89348(17) 0.0550(5) Uani d . 1 . . S S1 0.83816(7) 0.42719(5) 0.56027(7) 0.0673(3) Uani d . 1 . . S S2 0.48421(6) 0.40244(4) 0.45975(6) 0.0530(3) Uani d . 1 . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_12 _atom_site_aniso_U_13 _atom_site_aniso_U_23 C1 0.0575(18) 0.0556(18) 0.0530(16) -0.0068(14) 0.0203(13) -0.0060(12) C2 0.0538(17) 0.0595(18) 0.0506(15) -0.0040(14) 0.0190(13) -0.0061(13) C3 0.0528(16) 0.0364(14) 0.0466(14) 0.0020(11) 0.0188(12) -0.0001(10) C4 0.0539(17) 0.0405(14) 0.0480(14) 0.0007(12) 0.0192(12) -0.0021(11) C5 0.0592(18) 0.0456(16) 0.0488(14) -0.0017(13) 0.0221(13) -0.0006(11) C6 0.0585(19) 0.074(2) 0.0582(17) -0.0113(16) 0.0242(14) -0.0108(15) C7 0.058(2) 0.111(3) 0.090(3) -0.009(2) 0.0102(19) 0.014(2) C8 0.067(3) 0.148(5) 0.091(3) -0.006(3) 0.009(2) 0.010(3) C9 0.068(3) 0.158(5) 0.086(3) -0.024(3) 0.015(2) -0.033(3) C10 0.089(4) 0.144(5) 0.182(6) -0.054(4) -0.014(4) 0.007(4) C11 0.095(3) 0.111(4) 0.120(4) -0.040(3) -0.011(3) 0.021(3) C12 0.0574(17) 0.0532(17) 0.0459(14) -0.0032(13) 0.0262(13) -0.0028(12) C13 0.117(3) 0.0527(19) 0.0595(18) -0.0032(18) 0.0478(19) -0.0003(14) C14 0.134(4) 0.056(2) 0.087(2) -0.013(2) 0.061(3) -0.0166(18) C15 0.119(3) 0.083(3) 0.082(2) -0.027(2) 0.055(2) -0.036(2) C16 0.104(3) 0.105(3) 0.0460(17) -0.017(2) 0.0309(18) -0.0122(18) C17 0.077(2) 0.068(2) 0.0514(17) -0.0019(16) 0.0264(16) 0.0066(14) C18 0.0420(14) 0.0391(14) 0.0463(14) 0.0000(11) 0.0162(11) -0.0006(10) C19 0.0510(17) 0.0405(14) 0.0465(14) 0.0014(12) 0.0166(12) 0.0025(10) C20 0.0515(16) 0.0370(13) 0.0466(14) -0.0008(11) 0.0182(12) -0.0035(10) C21 0.0478(16) 0.0500(17) 0.0530(16) 0.0010(12) 0.0179(13) 0.0009(12) C22 0.0507(16) 0.0470(15) 0.0463(14) -0.0022(12) 0.0179(12) -0.0016(11) C23 0.0610(19) 0.0443(16) 0.0569(16) 0.0002(13) 0.0237(14) -0.0050(12) C24 0.071(2) 0.066(2) 0.0547(17) -0.0014(16) 0.0256(16) -0.0119(14) C25 0.082(2) 0.073(2) 0.0495(16) -0.0124(17) 0.0271(16) 0.0051(15) C26 0.100(3) 0.0525(19) 0.072(2) -0.0107(17) 0.0353(19) 0.0079(15) C27 0.086(2) 0.0457(16) 0.0592(17) -0.0053(15) 0.0305(16) -0.0047(13) C28 0.050(2) 0.174(5) 0.078(3) -0.006(3) 0.0180(19) 0.017(3) C29 0.101(5) 0.208(10) 0.073(6) -0.018(6) 0.005(6) -0.045(7) C30 0.148(9) 0.126(8) 0.206(11) -0.035(7) 0.017(7) -0.010(8) C31 0.27(2) 0.25(2) 0.28(2) -0.034(19) 0.07(2) -0.012(19) C29' 0.101(5) 0.208(10) 0.073(6) -0.018(6) 0.005(6) -0.045(7) C30' 0.148(9) 0.126(8) 0.206(11) -0.035(7) 0.017(7) -0.010(8) C31' 0.24(3) 0.22(3) 0.23(3) 0.00(2) 0.07(3) -0.03(2) F1 0.133(2) 0.1177(18) 0.0588(11) -0.0237(15) 0.0443(13) 0.0108(11) N1 0.0489(14) 0.0494(13) 0.0464(12) -0.0013(10) 0.0201(10) -0.0026(9) N2 0.0431(13) 0.0554(14) 0.0492(13) -0.0015(10) 0.0125(10) -0.0003(10) N3 0.0491(16) 0.109(2) 0.0588(15) -0.0030(14) 0.0213(12) 0.0037(14) O1 0.0544(12) 0.0664(13) 0.0432(10) -0.0070(10) 0.0136(9) -0.0076(9) S1 0.0562(5) 0.0893(7) 0.0620(5) -0.0049(4) 0.0264(4) -0.0186(4) S2 0.0561(5) 0.0612(5) 0.0416(4) -0.0025(3) 0.0150(3) -0.0022(3) loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' N N 0.0061 0.0033 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' F F 0.0171 0.0103 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' S S 0.1246 0.1234 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle C6 C1 C2 115.0(2) C6 C1 S1 107.2(2) C2 C1 S1 109.8(2) C6 C1 H1 108.2 C2 C1 H1 108.2 S1 C1 H1 108.2 C3 C2 C1 112.2(2) C3 C2 H2A 109.2 C1 C2 H2A 109.2 C3 C2 H2B 109.2 C1 C2 H2B 109.2 H2A C2 H2B 107.9 C4 C3 C18 111.5(2) C4 C3 C2 123.8(3) C18 C3 C2 124.7(2) C3 C4 C5 129.0(3) C3 C4 S2 112.4(2) C5 C4 S2 118.5(2) C4 C5 C12 113.0(2) C4 C5 S1 111.24(19) C12 C5 S1 107.9(2) C4 C5 H5 108.2 C12 C5 H5 108.2 S1 C5 H5 108.2 C11 C6 C7 116.4(4) C11 C6 C1 120.3(3) C7 C6 C1 123.2(3) C6 C7 C8 120.9(4) C6 C7 H7 119.6 C8 C7 H7 119.6 C9 C8 C7 121.9(5) C9 C8 H8 119.0 C7 C8 H8 119.0 C10 C9 C8 118.4(5) C10 C9 H9 120.8 C8 C9 H9 120.8 C9 C10 C11 121.0(5) C9 C10 H10 119.5 C11 C10 H10 119.5 C6 C11 C10 121.3(5) C6 C11 H11 119.3 C10 C11 H11 119.3 C13 C12 C17 118.7(3) C13 C12 C5 120.8(2) C17 C12 C5 120.6(3) C12 C13 C14 120.8(3) C12 C13 H13 119.6 C14 C13 H13 119.6 C15 C14 C13 119.7(4) C15 C14 H14 120.1 C13 C14 H14 120.1 C16 C15 C14 120.4(3) C16 C15 H15 119.8 C14 C15 H15 119.8 C15 C16 C17 120.1(3) C15 C16 H16 120.0 C17 C16 H16 120.0 C12 C17 C16 120.4(3) C12 C17 H17 119.8 C16 C17 H17 119.8 C19 C18 C20 117.9(2) C19 C18 C3 113.1(2) C20 C18 C3 128.8(2) N2 C19 C18 127.6(2) N2 C19 S2 120.8(2) C18 C19 S2 111.7(2) O1 C20 N1 119.7(2) O1 C20 C18 126.9(3) N1 C20 C18 113.3(2) N2 C21 N3 119.0(3) N2 C21 N1 123.7(3) N3 C21 N1 117.3(2) C27 C22 C23 120.8(3) C27 C22 N1 118.4(2) C23 C22 N1 120.7(2) C22 C23 C24 119.8(3) C22 C23 H23 120.1 C24 C23 H23 120.1 C25 C24 C23 118.3(3) C25 C24 H24 120.8 C23 C24 H24 120.8 C24 C25 F1 118.8(3) C24 C25 C26 123.2(3) F1 C25 C26 118.0(3) C25 C26 C27 118.3(3) C25 C26 H26 120.9 C27 C26 H26 120.9 C22 C27 C26 119.6(3) C22 C27 H27 120.2 C26 C27 H27 120.2 N3 C28 C29 119.1(6) N3 C28 C29' 105.3(7) C29 C28 C29' 29.7(6) N3 C28 H28A 107.5 C29 C28 H28A 107.5 C29' C28 H28A 136.5 N3 C28 H28B 107.5 C29 C28 H28B 107.5 C29' C28 H28B 89.2 H28A C28 H28B 107.0 N3 C28 H28C 110.7 C29 C28 H28C 82.1 C29' C28 H28C 111.7 H28A C28 H28C 28.6 H28B C28 H28C 128.6 N3 C28 H28D 111.1 C29 C28 H28D 120.3 C29' C28 H28D 109.1 H28A C28 H28D 84.7 H28B C28 H28D 22.8 H28C C28 H28D 108.9 C28 C29 C30 104.2(8) C28 C29 H29A 110.9 C30 C29 H29A 110.9 C28 C29 H29B 110.9 C30 C29 H29B 110.9 H29A C29 H29B 108.9 C29 C30 C31 99.0(12) C29 C30 H30A 112.0 C31 C30 H30A 112.0 C29 C30 H30B 112.0 C31 C30 H30B 112.0 H30A C30 H30B 109.6 C30' C29' C28 119.6(12) C30' C29' H29C 107.4 C28 C29' H29C 107.4 C30' C29' H29D 107.4 C28 C29' H29D 107.4 H29C C29' H29D 107.0 C31' C30' C29' 119.9(18) C31' C30' H30C 107.4 C29' C30' H30C 107.4 C31' C30' H30D 107.4 C29' C30' H30D 107.4 H30C C30' H30D 106.9 C30' C31' H31D 109.5 C30' C31' H31E 109.5 H31D C31' H31E 109.5 C30' C31' H31F 109.5 H31D C31' H31F 109.5 H31E C31' H31F 109.5 C21 N1 C20 122.8(2) C21 N1 C22 119.5(2) C20 N1 C22 117.2(2) C21 N2 C19 114.1(2) C21 N3 C28 124.7(3) C21 N3 H3 117.6 C28 N3 H3 117.6 C5 S1 C1 99.07(13) C19 S2 C4 91.32(13) loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance C1 C6 1.503(4) C1 C2 1.523(4) C1 S1 1.823(3) C1 H1 0.9800 C2 C3 1.508(4) C2 H2A 0.9700 C2 H2B 0.9700 C3 C4 1.360(4) C3 C18 1.440(4) C4 C5 1.504(4) C4 S2 1.745(3) C5 C12 1.513(4) C5 S1 1.814(3) C5 H5 0.9800 C6 C11 1.360(6) C6 C7 1.372(5) C7 C8 1.375(5) C7 H7 0.9300 C8 C9 1.333(7) C8 H8 0.9300 C9 C10 1.333(8) C9 H9 0.9300 C10 C11 1.389(7) C10 H10 0.9300 C11 H11 0.9300 C12 C13 1.375(4) C12 C17 1.379(4) C13 C14 1.386(4) C13 H13 0.9300 C14 C15 1.365(6) C14 H14 0.9300 C15 C16 1.360(5) C15 H15 0.9300 C16 C17 1.387(5) C16 H16 0.9300 C17 H17 0.9300 C18 C19 1.373(4) C18 C20 1.433(4) C19 N2 1.369(4) C19 S2 1.719(3) C20 O1 1.221(3) C20 N1 1.423(4) C21 N2 1.313(4) C21 N3 1.352(4) C21 N1 1.381(4) C22 C27 1.369(4) C22 C23 1.372(4) C22 N1 1.444(3) C23 C24 1.381(4) C23 H23 0.9300 C24 C25 1.347(5) C24 H24 0.9300 C25 F1 1.357(3) C25 C26 1.367(5) C26 C27 1.378(4) C26 H26 0.9300 C27 H27 0.9300 C28 N3 1.432(5) C28 C29 1.457(8) C28 C29' 1.539(10) C28 H28A 0.9700 C28 H28B 0.9700 C28 H28C 0.9700 C28 H28D 0.9700 C29 C30 1.500(9) C29 H29A 0.9700 C29 H29B 0.9700 C30 C31 1.565(10) C30 H30A 0.9700 C30 H30B 0.9700 C31 H31A 0.9600 C31 H31B 0.9600 C31 H31C 0.9600 C29' C30' 1.535(10) C29' H29C 0.9700 C29' H29D 0.9700 C30' C31' 1.522(10) C30' H30C 0.9700 C30' H30D 0.9700 C31' H31D 0.9600 C31' H31E 0.9600 C31' H31F 0.9600 N3 H3 0.8600 loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_site_symmetry_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA C5 H5 N2 3_666 0.98 2.60 3.507(4) 154.0 loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion C6 C1 C2 C3 -177.7(3) S1 C1 C2 C3 -56.7(3) C1 C2 C3 C4 22.9(4) C1 C2 C3 C18 -155.1(3) C18 C3 C4 C5 178.1(3) C2 C3 C4 C5 -0.1(4) C18 C3 C4 S2 1.8(3) C2 C3 C4 S2 -176.4(2) C3 C4 C5 C12 135.7(3) S2 C4 C5 C12 -48.1(3) C3 C4 C5 S1 14.2(4) S2 C4 C5 S1 -169.64(14) C2 C1 C6 C11 -136.7(4) S1 C1 C6 C11 100.8(4) C2 C1 C6 C7 42.4(4) S1 C1 C6 C7 -80.0(4) C11 C6 C7 C8 -1.5(6) C1 C6 C7 C8 179.4(4) C6 C7 C8 C9 -0.3(7) C7 C8 C9 C10 1.3(9) C8 C9 C10 C11 -0.6(10) C7 C6 C11 C10 2.2(8) C1 C6 C11 C10 -178.6(5) C9 C10 C11 C6 -1.2(10) C4 C5 C12 C13 -55.5(4) S1 C5 C12 C13 67.8(3) C4 C5 C12 C17 123.5(3) S1 C5 C12 C17 -113.1(3) C17 C12 C13 C14 -0.8(5) C5 C12 C13 C14 178.3(3) C12 C13 C14 C15 0.7(6) C13 C14 C15 C16 -0.3(7) C14 C15 C16 C17 -0.1(7) C13 C12 C17 C16 0.5(5) C5 C12 C17 C16 -178.6(3) C15 C16 C17 C12 0.0(6) C4 C3 C18 C19 -2.4(3) C2 C3 C18 C19 175.8(3) C4 C3 C18 C20 172.6(3) C2 C3 C18 C20 -9.2(4) C20 C18 C19 N2 6.6(4) C3 C18 C19 N2 -177.8(2) C20 C18 C19 S2 -173.70(19) C3 C18 C19 S2 2.0(3) C19 C18 C20 O1 176.8(3) C3 C18 C20 O1 1.9(4) C19 C18 C20 N1 -1.5(3) C3 C18 C20 N1 -176.3(2) C27 C22 C23 C24 -0.1(5) N1 C22 C23 C24 179.8(3) C22 C23 C24 C25 -2.2(5) C23 C24 C25 F1 -179.0(3) C23 C24 C25 C26 2.5(6) C24 C25 C26 C27 -0.3(6) F1 C25 C26 C27 -178.8(3) C23 C22 C27 C26 2.2(5) N1 C22 C27 C26 -177.6(3) C25 C26 C27 C22 -2.0(5) N3 C28 C29 C30 65.7(10) C29' C28 C29 C30 -2.7(19) C28 C29 C30 C31 168.9(12) N3 C28 C29' C30' -173.1(15) C29 C28 C29' C30' -50.5(16) C28 C29' C30' C31' 122(2) N2 C21 N1 C20 7.0(4) N3 C21 N1 C20 -171.5(3) N2 C21 N1 C22 -165.4(3) N3 C21 N1 C22 16.1(4) O1 C20 N1 C21 176.9(2) C18 C20 N1 C21 -4.7(3) O1 C20 N1 C22 -10.5(3) C18 C20 N1 C22 167.9(2) C27 C22 N1 C21 74.6(4) C23 C22 N1 C21 -105.3(3) C27 C22 N1 C20 -98.3(3) C23 C22 N1 C20 81.8(3) N3 C21 N2 C19 176.3(3) N1 C21 N2 C19 -2.2(4) C18 C19 N2 C21 -4.7(4) S2 C19 N2 C21 175.6(2) N2 C21 N3 C28 -1.8(5) N1 C21 N3 C28 176.8(4) C29 C28 N3 C21 75.9(6) C29' C28 N3 C21 104.4(9) C4 C5 S1 C1 -41.1(2) C12 C5 S1 C1 -165.49(19) C6 C1 S1 C5 -170.4(2) C2 C1 S1 C5 64.0(2) N2 C19 S2 C4 179.0(2) C18 C19 S2 C4 -0.8(2) C3 C4 S2 C19 -0.6(2) C5 C4 S2 C19 -177.4(2) _cod_database_fobs_code 2216643 _journal_paper_doi 10.1107/S1600536807060850