#------------------------------------------------------------------------------ #$Date: 2021-09-06 15:30:46 +0300 (Mon, 06 Sep 2021) $ #$Revision: 268943 $ #$URL: file:///home/coder/svn-repositories/cod/cif/7/15/81/7158167.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/ # # All data on this site have been placed in the public domain by the # contributors. # data_7158167 loop_ _publ_author_name 'Wu, Hao' 'Wang, Yi-Chun' 'Shatskiy, Andrey' 'Li, Qiu-Yan' 'Liu, Jian-Quan' 'K\"ark\"as, Markus D' 'Wang, Xiang-Shan' _publ_section_title ; Modular synthesis of 3-substituted isocoumarins via silver-catalyzed aerobic oxidation/6-endo heterocyclization of ortho-alkynylbenzaldehydes. ; _journal_issue 30 _journal_name_full 'Organic & biomolecular chemistry' _journal_page_first 6657 _journal_page_last 6664 _journal_paper_doi 10.1039/d1ob01065d _journal_volume 19 _journal_year 2021 _chemical_formula_sum 'C16 H12 O3' _chemical_formula_weight 252.26 _space_group_IT_number 2 _space_group_name_Hall '-P 1' _space_group_name_H-M_alt 'P -1' _atom_sites_solution_hydrogens geom _atom_sites_solution_primary direct _atom_sites_solution_secondary difmap _audit_block_doi 10.5517/ccdc.csd.cc26x0x2 _audit_creation_method SHELXL-97 _audit_update_record ; 2020-12-28 deposited with the CCDC. 2021-07-09 downloaded from the CCDC. ; _cell_angle_alpha 76.201(3) _cell_angle_beta 81.124(3) _cell_angle_gamma 73.395(3) _cell_formula_units_Z 2 _cell_length_a 7.0451(17) _cell_length_b 7.3918(17) _cell_length_c 12.782(3) _cell_measurement_temperature 296(2) _cell_volume 616.8(3) _computing_structure_refinement 'SHELXL-97 (Sheldrick, 1997)' _computing_structure_solution 'SHELXS-97 (Sheldrick, 1990)' _diffrn_ambient_temperature 296(2) _diffrn_measured_fraction_theta_full 0.989 _diffrn_measured_fraction_theta_max 0.989 _diffrn_radiation_monochromator graphite _diffrn_radiation_source 'fine-focus sealed tube' _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_reflns_av_R_equivalents 0.0195 _diffrn_reflns_av_sigmaI/netI 0.0167 _diffrn_reflns_limit_h_max 8 _diffrn_reflns_limit_h_min -8 _diffrn_reflns_limit_k_max 6 _diffrn_reflns_limit_k_min -8 _diffrn_reflns_limit_l_max 12 _diffrn_reflns_limit_l_min -15 _diffrn_reflns_number 6292 _diffrn_reflns_theta_full 25.02 _diffrn_reflns_theta_max 25.02 _diffrn_reflns_theta_min 2.94 _exptl_absorpt_coefficient_mu 0.094 _exptl_crystal_density_diffrn 1.358 _exptl_crystal_density_method 'not measured' _exptl_crystal_F_000 264 _refine_diff_density_max 0.159 _refine_diff_density_min -0.253 _refine_diff_density_rms 0.066 _refine_ls_extinction_coef 0.30(2) _refine_ls_extinction_expression Fc^*^=kFc[1+0.001xFc^2^\l^3^/sin(2\q)]^-1/4^ _refine_ls_extinction_method SHELXL _refine_ls_goodness_of_fit_ref 1.082 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 173 _refine_ls_number_reflns 2159 _refine_ls_number_restraints 0 _refine_ls_restrained_S_all 1.082 _refine_ls_R_factor_all 0.0507 _refine_ls_R_factor_gt 0.0454 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'calc w=1/[\s^2^(Fo^2^)+(0.0703P)^2^+0.1220P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1218 _refine_ls_wR_factor_ref 0.1317 _reflns_number_gt 1918 _reflns_number_total 2159 _reflns_threshold_expression >2sigma(I) _cod_data_source_file d1ob01065d2.cif _cod_data_source_block a _cod_depositor_comments 'Adding full bibliography for 7158167.cif.' _cod_database_code 7158167 loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x, -y, -z' loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_symmetry_multiplicity _atom_site_calc_flag _atom_site_refinement_flags _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.58702(13) 0.40300(14) 0.32350(8) 0.0452(3) Uani 1 1 d . . . O2 O 0.85798(15) 0.27584(17) 0.40806(9) 0.0591(4) Uani 1 1 d . . . O3 O 0.59993(16) -0.05246(16) 0.78640(8) 0.0553(3) Uani 1 1 d . . . C1 C 0.8066(3) -0.0897(3) 0.79660(14) 0.0618(5) Uani 1 1 d . . . H1A H 0.8366 -0.1679 0.8666 0.093 Uiso 1 1 calc R . . H1B H 0.8403 0.0302 0.7885 0.093 Uiso 1 1 calc R . . H1C H 0.8821 -0.1564 0.7416 0.093 Uiso 1 1 calc R . . C2 C 0.5303(2) 0.05614(19) 0.69162(11) 0.0433(4) Uani 1 1 d . . . C3 C 0.3249(2) 0.0967(2) 0.68740(12) 0.0485(4) Uani 1 1 d . . . H3A H 0.2468 0.0511 0.7479 0.058 Uiso 1 1 calc R . . C4 C 0.2364(2) 0.2022(2) 0.59603(11) 0.0464(4) Uani 1 1 d . . . H4A H 0.0996 0.2271 0.5950 0.056 Uiso 1 1 calc R . . C5 C 0.35142(19) 0.27309(18) 0.50372(11) 0.0375(3) Uani 1 1 d . . . C6 C 0.2680(2) 0.38210(19) 0.40521(11) 0.0413(4) Uani 1 1 d . . . H6A H 0.1314 0.4111 0.4015 0.050 Uiso 1 1 calc R . . C7 C 0.38415(19) 0.44254(18) 0.31865(11) 0.0393(3) Uani 1 1 d . . . C8 C 0.6803(2) 0.30139(19) 0.41413(11) 0.0415(3) Uani 1 1 d . . . C9 C 0.55598(19) 0.23244(18) 0.50913(10) 0.0373(3) Uani 1 1 d . . . C10 C 0.6467(2) 0.12408(19) 0.60220(11) 0.0415(4) Uani 1 1 d . . . H10A H 0.7835 0.0982 0.6038 0.050 Uiso 1 1 calc R . . C11 C 0.3228(2) 0.55227(19) 0.21170(11) 0.0434(4) Uani 1 1 d . . . C12 C 0.1296(2) 0.5827(2) 0.18610(13) 0.0558(4) Uani 1 1 d . . . H12A H 0.0383 0.5331 0.2371 0.067 Uiso 1 1 calc R . . C13 C 0.0720(3) 0.6858(3) 0.08575(15) 0.0703(5) Uani 1 1 d . . . H13A H -0.0575 0.7053 0.0697 0.084 Uiso 1 1 calc R . . C14 C 0.2059(3) 0.7597(3) 0.00954(14) 0.0747(6) Uani 1 1 d . . . H14A H 0.1671 0.8286 -0.0581 0.090 Uiso 1 1 calc R . . C15 C 0.3953(3) 0.7315(3) 0.03349(14) 0.0736(6) Uani 1 1 d . . . H15A H 0.4853 0.7821 -0.0180 0.088 Uiso 1 1 calc R . . C16 C 0.4556(3) 0.6282(2) 0.13393(13) 0.0575(4) Uani 1 1 d . . . H16A H 0.5855 0.6098 0.1492 0.069 Uiso 1 1 calc R . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0368(6) 0.0543(6) 0.0411(6) -0.0021(4) 0.0036(4) -0.0167(4) O2 0.0351(6) 0.0816(8) 0.0570(7) -0.0010(5) 0.0029(4) -0.0240(5) O3 0.0591(7) 0.0629(7) 0.0393(6) 0.0014(5) -0.0065(5) -0.0173(5) C1 0.0641(11) 0.0645(10) 0.0513(9) -0.0039(7) -0.0144(8) -0.0102(8) C2 0.0519(9) 0.0426(7) 0.0363(7) -0.0084(6) -0.0003(6) -0.0153(6) C3 0.0473(8) 0.0547(8) 0.0414(8) -0.0054(6) 0.0089(6) -0.0205(6) C4 0.0356(7) 0.0546(8) 0.0467(8) -0.0064(6) 0.0055(6) -0.0163(6) C5 0.0367(7) 0.0381(7) 0.0392(7) -0.0091(5) 0.0023(5) -0.0143(5) C6 0.0343(7) 0.0439(7) 0.0453(8) -0.0066(6) -0.0010(6) -0.0130(6) C7 0.0387(7) 0.0382(7) 0.0416(7) -0.0082(5) 0.0004(6) -0.0129(5) C8 0.0365(7) 0.0462(7) 0.0422(7) -0.0075(6) 0.0016(5) -0.0156(6) C9 0.0369(7) 0.0379(7) 0.0392(7) -0.0103(5) 0.0029(5) -0.0144(5) C10 0.0368(7) 0.0455(7) 0.0437(8) -0.0096(6) -0.0021(6) -0.0136(6) C11 0.0493(8) 0.0385(7) 0.0404(8) -0.0072(6) -0.0003(6) -0.0110(6) C12 0.0557(9) 0.0574(9) 0.0514(9) -0.0010(7) -0.0080(7) -0.0171(7) C13 0.0709(12) 0.0766(12) 0.0587(10) 0.0019(8) -0.0202(9) -0.0174(9) C14 0.0881(14) 0.0771(12) 0.0466(9) 0.0062(8) -0.0169(9) -0.0123(10) C15 0.0841(14) 0.0786(12) 0.0448(9) 0.0056(8) 0.0081(9) -0.0227(10) C16 0.0565(10) 0.0627(10) 0.0469(9) -0.0019(7) 0.0031(7) -0.0171(7) loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C8 O1 C7 123.27(10) . . ? C2 O3 C1 117.68(12) . . ? O3 C1 H1A 109.5 . . ? O3 C1 H1B 109.5 . . ? H1A C1 H1B 109.5 . . ? O3 C1 H1C 109.5 . . ? H1A C1 H1C 109.5 . . ? H1B C1 H1C 109.5 . . ? O3 C2 C10 124.87(13) . . ? O3 C2 C3 115.57(12) . . ? C10 C2 C3 119.56(13) . . ? C4 C3 C2 121.35(13) . . ? C4 C3 H3A 119.3 . . ? C2 C3 H3A 119.3 . . ? C3 C4 C5 120.31(13) . . ? C3 C4 H4A 119.8 . . ? C5 C4 H4A 119.8 . . ? C9 C5 C4 117.79(13) . . ? C9 C5 C6 119.26(12) . . ? C4 C5 C6 122.95(13) . . ? C7 C6 C5 120.75(13) . . ? C7 C6 H6A 119.6 . . ? C5 C6 H6A 119.6 . . ? C6 C7 O1 120.29(12) . . ? C6 C7 C11 127.46(13) . . ? O1 C7 C11 112.25(11) . . ? O2 C8 O1 116.97(12) . . ? O2 C8 C9 125.83(13) . . ? O1 C8 C9 117.20(12) . . ? C5 C9 C10 121.99(12) . . ? C5 C9 C8 119.22(12) . . ? C10 C9 C8 118.78(12) . . ? C2 C10 C9 119.00(13) . . ? C2 C10 H10A 120.5 . . ? C9 C10 H10A 120.5 . . ? C16 C11 C12 118.31(14) . . ? C16 C11 C7 120.96(14) . . ? C12 C11 C7 120.74(13) . . ? C13 C12 C11 120.73(16) . . ? C13 C12 H12A 119.6 . . ? C11 C12 H12A 119.6 . . ? C14 C13 C12 120.17(18) . . ? C14 C13 H13A 119.9 . . ? C12 C13 H13A 119.9 . . ? C15 C14 C13 119.79(16) . . ? C15 C14 H14A 120.1 . . ? C13 C14 H14A 120.1 . . ? C14 C15 C16 120.77(17) . . ? C14 C15 H15A 119.6 . . ? C16 C15 H15A 119.6 . . ? C11 C16 C15 120.23(17) . . ? C11 C16 H16A 119.9 . . ? C15 C16 H16A 119.9 . . ? loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 C8 1.3695(17) . ? O1 C7 1.3827(16) . ? O2 C8 1.2043(17) . ? O3 C2 1.3592(17) . ? O3 C1 1.423(2) . ? C1 H1A 0.9600 . ? C1 H1B 0.9600 . ? C1 H1C 0.9600 . ? C2 C10 1.3799(19) . ? C2 C3 1.398(2) . ? C3 C4 1.369(2) . ? C3 H3A 0.9300 . ? C4 C5 1.4055(19) . ? C4 H4A 0.9300 . ? C5 C9 1.3948(19) . ? C5 C6 1.4332(19) . ? C6 C7 1.3369(19) . ? C6 H6A 0.9300 . ? C7 C11 1.4719(19) . ? C8 C9 1.4606(18) . ? C9 C10 1.3974(19) . ? C10 H10A 0.9300 . ? C11 C16 1.388(2) . ? C11 C12 1.392(2) . ? C12 C13 1.381(2) . ? C12 H12A 0.9300 . ? C13 C14 1.376(3) . ? C13 H13A 0.9300 . ? C14 C15 1.362(3) . ? C14 H14A 0.9300 . ? C15 C16 1.388(2) . ? C15 H15A 0.9300 . ? C16 H16A 0.9300 . ? loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion _geom_torsion_site_symmetry_1 _geom_torsion_site_symmetry_2 _geom_torsion_site_symmetry_3 _geom_torsion_site_symmetry_4 _geom_torsion_publ_flag C1 O3 C2 C10 3.9(2) . . . . ? C1 O3 C2 C3 -176.96(12) . . . . ? O3 C2 C3 C4 -178.99(12) . . . . ? C10 C2 C3 C4 0.2(2) . . . . ? C2 C3 C4 C5 -0.2(2) . . . . ? C3 C4 C5 C9 -0.1(2) . . . . ? C3 C4 C5 C6 179.13(12) . . . . ? C9 C5 C6 C7 0.9(2) . . . . ? C4 C5 C6 C7 -178.39(13) . . . . ? C5 C6 C7 O1 -1.0(2) . . . . ? C5 C6 C7 C11 178.91(12) . . . . ? C8 O1 C7 C6 0.43(19) . . . . ? C8 O1 C7 C11 -179.47(11) . . . . ? C7 O1 C8 O2 179.76(12) . . . . ? C7 O1 C8 C9 0.22(18) . . . . ? C4 C5 C9 C10 0.4(2) . . . . ? C6 C5 C9 C10 -178.89(11) . . . . ? C4 C5 C9 C8 179.08(12) . . . . ? C6 C5 C9 C8 -0.22(19) . . . . ? O2 C8 C9 C5 -179.80(13) . . . . ? O1 C8 C9 C5 -0.30(18) . . . . ? O2 C8 C9 C10 -1.1(2) . . . . ? O1 C8 C9 C10 178.41(11) . . . . ? O3 C2 C10 C9 179.18(12) . . . . ? C3 C2 C10 C9 0.0(2) . . . . ? C5 C9 C10 C2 -0.4(2) . . . . ? C8 C9 C10 C2 -179.03(11) . . . . ? C6 C7 C11 C16 171.03(14) . . . . ? O1 C7 C11 C16 -9.08(19) . . . . ? C6 C7 C11 C12 -8.9(2) . . . . ? O1 C7 C11 C12 171.02(12) . . . . ? C16 C11 C12 C13 0.1(2) . . . . ? C7 C11 C12 C13 179.96(14) . . . . ? C11 C12 C13 C14 0.1(3) . . . . ? C12 C13 C14 C15 -0.3(3) . . . . ? C13 C14 C15 C16 0.3(3) . . . . ? C12 C11 C16 C15 0.0(2) . . . . ? C7 C11 C16 C15 -179.94(14) . . . . ? C14 C15 C16 C11 -0.1(3) . . . . ?